PREPARATION AND DERIVATIVES OF N SUBSTITUTED GLYCINO NITRILES
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CIBA PHARMACEUTICAL PRODUCTS, DIVISION OF CHEMISTRY, RESEARCH DEPARTMENT, SUMMIT, NJ, EUA
CORNELL UNIVERSITY, DEPARTMENT OF BIOCHEMISTRY, MEDICAL COLLEGE, NEW YORK, NY, EUA
LABORATORIOS SYNTEX, CD. MEXICO, DF, MEX
CORNELL UNIVERSITY, DEPARTMENT OF BIOCHEMISTRY, MEDICAL COLLEGE, NEW YORK, NY, EUA
LABORATORIOS SYNTEX, CD. MEXICO, DF, MEX
Abstract
An improved procedure for the cyanomethylation of secondary amines has been described, and the behavior of the resulting N,N-disubstituted glycinonitriles toward acid has been investigated. N-Benzyl-N-phenylglycinonitrile was converted into the correspond